Biome Protect

30 day supply

Finally, a Gut Health Formula That You Can Trust

Biome Protect

30 day supply

Finally, a Gut Health Formula That You Can Trust

After years of trial and error, you can trust this research-backed 4-in-1 blend to support your gut, immunity, and whole-body health without the guesswork.

  • Feel normal digestion again

  • Trust your immune system to protect you

  • Think clearly and feel like yourself

  • Let your good bacteria thrive

  • Strengthen your gut barrier

Warning: If taking a blood thinner or anti-coagulant medication, consult a healthcare practitioner before use.

Supplement Facts

Serving Size: 2 Vegetarian Capsules

Servings Per Container: 30

Amount Per Serving % Daily Value
Tributyrin (as CoreBiome®) 300mg  *
Bacillus coagulans (Probiotic) 2 billion CFU  *
Pomegranate (Punica granatum) Fruit Extract 50mg  *
Grape (Vitis vinifera) Seed Extract 50mg  *
Cranberry (Vaccinium macrocarpon) Fruit Extract 50mg  *
Blueberry (Vaccinium corymbosum) Fruit Extract 50mg  *
FortiPhage™ Prebiotic Blend ECCR 664-1 (Myoviridae), ECML-117 (Myoviridae), and ECML-359 (Myoviridae) 15mg  *
†Percent Daily Value based on a 2,000 calorie diet. *Daily Value not established.
Other Ingredients: Hydroxypropyl methylcellulose, Microcrystalline cellulose, Magnesium stearate, Silicon dioxide
Recommended Use: Take 2 capsules once a day, or as directed by your healthcare practitioner.
Warning: Consult your physician before use if you are pregnant, nursing, have a medical condition, or are taking any medication. Keep out of reach of children. Store at room temperature.
FortiPhage™ is a trademark of Intralytix, Inc.
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NOURISH YOUR MICROBIOME

Your Good Bacteria, Finally Thriving

FortiPhage™ and Bacillus coagulans work together to promote beneficial bacteria growth while reducing harmful microbes.

FORTIFY YOUR DEFENSES

Feel Safe. Your Immune System Has You.

This unique combination of probiotics, prebiotics, and polyphenols supports a robust immune response and helps protect against pathogens.

YOUR DIGESTION, WORKING RIGHT

No More Bloating. No More Guessing.

Our 4-in-1 blend supports gut barrier function, reducing bloating, gas, and digestive discomfort.

YOUR MIND, CLEAR AGAIN

Think Clearly. Feel Like Yourself.

Butyrate and polyphenols from cranberry, blueberry, pomegranate, and grape support cognitive function and mood.

Powerful Nutrients & Vitamins

TRIBUTYRIN (as CoreBiome®) (300 mg)

TRIBUTYRIN (as CoreBiome®) (300 mg)

Your gut cells need butyrate like your lungs need oxygen. CoreBiome® is the only form proven to reach your colon intact. Real fuel for real relief.

BACILLUS COAGULANS (as LactoSpore®) (2 Billion CFU)

BACILLUS COAGULANS (as LactoSpore®) (2 Billion CFU)

You already know most probiotics die in stomach acid. This spore-forming strain makes it through. Research confirms what you need: balanced digestion, steady immunity, clear thinking.

FORTIPHAGE™ PREBIOTIC (15 mg)

FORTIPHAGE™ PREBIOTIC (15 mg)

You already know fiber supplements backfire. FortiPhage™ targets bad bacteria at just 15mg—no gas, no discomfort. Your gut gets what it needs without the suffering.

POLYPHENOL BLEND (200 mg)

POLYPHENOL BLEND (200 mg)

Pomegranate, grape, cranberry, blueberry—four researched sources working with your microbiome. They support your gut, your mind, your heart.

You Need Biome Protect If You're Tired of:

Bloating that ruins your favorite jeans

Never knowing when your gut will cooperate

Being too tired to show up for what matters

Brain fog during important conversations

Catching every bug your kids bring home

Skin that doesn't match how you eat

Fighting sugar cravings all day

Snapping at people you love

What You'll Finally Feel:

  • Comfortable digestion you can trust

  • Predictable bowel movements (what a relief)

  • Enough energy for your real life

  • Clear thinking when you need it

  • Confidence you won't get sick

  • Skin you feel good about

  • Steady blood sugar, fewer cravings

  • Yourself again—calm and capable

90-Day Money Back Guarantee

90-Day Money Back Guarantee

We're confident you'll love our products, but if you're not completely satisfied, we offer a 90-Day, 100% money-back guarantee on all purchases. Simply contact us for a full refund, no questions asked. Buy with confidence knowing you're covered by our guarantee.

The Adapt Naturals Standard

The Adapt Naturals Standard

In our increasingly toxic world, the last thing you want to worry about is a lot of artificial junk in your supplements. Adapt Naturals supplements are made with the cleanest possible ingredients, without gluten or GMOs. Our products are manufactured in a U.S. facility that meets the NSF's rigorous GMP regulatory standards.

Third-Party Lab-Tested with Transparent Results

Third-Party Lab-Tested with Transparent Results

We conduct third-party testing on all our products to verify their purity, potency, and safety. Most importantly, we transparently share these results with our customers by posting Certificates of Analysis (COAs) and test results directly on our website. We want you to have full confidence that you're getting exactly what you think you are with each purchase.

See Test Results

After trying everything, here's what finally works.

You've been let down before. Biome Protect has all four elements your gut needs—not just one or two. Prebiotics, probiotics, postbiotics, polyphenols. Research-backed and complete.

Here's what makes it different:

1. FortiPhage™ prebiotic (15mg vs. grams of fiber) - No bloating

2. LactoSpore® probiotic (spore-forming) - Survives stomach acid

3. CoreBiome® butyrate (tributyrin) - Reaches your colon intact

4. Polyphenol blend (4 sources) - Protects and nourishes

Your search ends here. Chris Kresser spent 15 years in clinical practice treating patients with your exact struggles. This formula is the result of that experience—everything you need, nothing you don't.

You're safe now.

Discover the Biome Protect Advantage

 
Competitors
Ingredients
Full-spectrum blend you can trust
Only 1 or 2 ingredients
Efficacy
Reaches intestines intact
Destroyed by stomach acid
Health focus
Holistic gut-brain support
Single-target approach
Convenience
Shelf-stable (no refrigeration worry)
Requires refrigeration
Clinical background
15 years proven in-clinic results
Limited real-world application
Validation
Third-party tested (we share results)
Unverified ingredients
Sustainability
Earth-friendly packaging
Excessive plastic waste
Founder
Functional Medicine expert you know
Marketers

Meet Chris Kresser, Your
Trusted Gut Health Expert

Founder & Functional Medicine Practitioner

  • 15+ years listening to patients with your exact struggles
  • Treats the cause, not just symptoms
  • Believes you deserve to feel normal again—not perfect, just good

Author & Educator

  • Pioneer in the field of ancestral health and nutrition
  • Trained more than 2,000 health practitioners in Functional Medicine
  • New York Times bestselling author of "The Paleo Cure" and "Unconventional Medicine"
Biome Protect

Upgrade Your Gut with Biome Protect

The Complete Microbiome Support You've Been Searching For

Get Healthier & Happier - Try Now

Good For You—And the Planet

You can't have healthy humans without a healthy planet. That's why Adapt Naturals is working toward zero plastic and landfill waste in our supply chain.

In the fall of 2023, we started transitioning our packaging to 100% compostable, stand-up pouches. They're made from cellulose (wood pulp) and are free of PLA, BPA, PFAS, phthalates, and other harmful chemicals. They're printed with non-toxic, compostable ink. The pouches are so clean and biodegradable that you can put them in your backyard or curbside compost bin!

Our sustainable packaging initiative will prevent over 120,000 plastic bottles from ending up in a landfill or the oceans. Thank you for being part of the solution and helping Adapt Naturals protect the beauty of our natural environment!

Your Questions Answered

For maintenance: Take 2 capsules daily.

For intensive support (if you're struggling with gut health symptoms): Start with 2 capsules daily. If well tolerated, increase to 2 capsules twice daily (4 total) for 6-8 weeks, or until symptoms improve significantly. Then switch to the maintenance regimen.

We suggest taking Biome Protect with meals when possible, but it may also be taken on an empty stomach.

No, Biome Protect is shelf-stable and does not require refrigeration. Store in a cool, dry place. One less thing to worry about.

Most people feel better within days.

Give it 30-60 days for the deeper shifts you're looking for. You can trust this is working, even on the days you don't notice anything. Your gut is healing.

Yes, Biome Protect is designed to complement other supplements safely. If you're taking any medications, consult with your healthcare provider before starting any new supplement regimen.

Yes, Biome Protect is formulated for safe, long-term use. The ingredients are naturally occurring compounds that support gut health and wellness. You can trust it as part of your daily routine.

If you are pregnant, nursing, or taking blood thinners or anti-coagulant medications, consult with your healthcare provider before using Biome Protect.

Yes, all Adapt Naturals products, including Biome Protect, undergo rigorous third-party testing for purity and potency. Most importantly, we transparently share these results with our customers by posting Certificates of Analysis (CoAs) and test results on our website. This level of openness is almost unheard of in the supplement industry. It allows you to see exactly what's in the product you're putting into your body. You can verify the quality for yourself. Click here to view the most recent CoA and test results.

  • 5 stars: 455 (72%)
  • 4 stars: 86 (14%)
  • 3 stars: 38 (6%)
  • 2 stars: 26 (4%)
  • 1 star: 27 (4%)
Some of the reviews shown are from related products the merchant grouped with this one.
K
Kelly Fischer
Thoughtfully Formulated

I’ve been really intentional about supporting my gut health lately, and Biome Protect has become one of those daily wellness habits that just makes sense for me. I love that it takes a more holistic approach with a blend of prebiotics, postbiotics, polyphenols, and other gut-supportive ingredients, rather than feeling like I’m just adding another supplement to the lineup.
I’ve been mixing it into my daily routine and genuinely love knowing I’m tending to my microbiome from a few different angles. I've been thinking of it as a little daily garden tending for my gut!

Hey Kelly,

Daily garden tending for your gut is genuinely one of the most perfect descriptions of what Biome Protect is designed to do and we are absolutely using that! The Bacillus coagulans the FortiPhage™ bacteriophage prebiotic the CoreBiome® tributyrin and the polyphenol blend from pomegranate grape cranberry and blueberry each tending a completely different part of the gut ecosystem every single day is exactly the holistic multi-angle approach Chris designed it around. We love that it just makes sense to you and thank you so much for sharing!

R
Rosalie Christiansen b
Biome Protect

This is an incredible product. This has worked for me when many others have not.

I have had a bulging, rock hard stomach for a long time. I had this experience once before when I had a mold infection. This time, my problem is not mold. It might be due to a drug response I had last winter. At any rate, I have had good results with Biome Protect. I added colostrum to my daily routine and it was a good thing. My problem is resolved and I am taking Biome Protect as a preventative.

Hey Rosalie,

A bulging rock hard stomach that resisted everything else and then Biome Protect plus Colostrum+ resolving it and now using both as a preventative going forward is exactly the combination Chris designed the Total Gut Reset protocol to deliver. The Bacillus coagulans the FortiPhage™ bacteriophage prebiotic the CoreBiome® tributyrin and the polyphenol blend from pomegranate grape cranberry and blueberry rebalancing the microbiome environment while the colostrum nourishes and repairs the gut lining from the other direction is such a powerful pairing. We are so glad you found what worked and thank you for sharing your story!

T
Toni Pensiero
Biome supplement

My husband has been on this for 2 months now and feels less bloated and more regular. Great product.

Hey Toni,

Two months of less bloating and better regularity for your husband is wonderful to hear and we are so glad it is making a real difference in his daily life! The CoreBiome® tributyrin fueling the colon cells directly plays a big role in that regularity improvement and the Bacillus coagulans the FortiPhage™ bacteriophage prebiotic and the polyphenol blend from pomegranate grape cranberry and blueberry are all working together to keep the gut environment balanced and thriving. Thank you so much for sharing on his behalf!

M
Marianna Ancona
Good product

Living with flatulence my whole life, and the more I age the more it gets worse, I really want this product to work. So far I believe I noticed a little difference, a small improvement, i’ve been using it for a 3 weeks now and I hope it gets better.

Hey Marianna,

Three weeks in and already noticing a small improvement is a really encouraging start and we are rooting hard for things to keep shifting! The Bacillus coagulans the FortiPhage™ bacteriophage prebiotic the CoreBiome® tributyrin and the polyphenol blend from pomegranate grape cranberry and blueberry all build with consistent use and the benefits really do compound over time. Gas and flatulence are often some of the last things to fully resolve as the microbiome rebalances so hang in there and give it the full 8 to 12 weeks. We believe this is going to keep getting better for you. Thank you for sharing!

R
Rachel K Kirby
What we've been looking for

I bought the Biome Protect for my husband who has Crohn's disease, and he like it so much that I bought it for myself as well.

Hey Rachel,

This is so sweet and honestly one of our favorite kinds of reviews! The photo you sent along made us truly smile! Biome Protect was formulated with people in mind who have real and persistent gut challenges. The 4-in-1 combination tends to resonate with people who have tried everything else. We hope you and your husband both continue to feel the full benefits and thank you so much for the support. This truly means the world to us!

E
E.K. Blackwell
Best product ever!

I have suffered with a disrupted gut for years. Probably before I even realized it. Decided to try the Bio-Avail along with the Biome Protect. It has worked great! Started to see a very noticeable improvement within the first week. I no longer suffer from the bloating after eating, The gas and belching has all but disappeared and I am only 3 weeks in with my first order. Customer for life!

Hey there,

This is amazing—thank you so much for sharing! We're thrilled to hear you're seeing such dramatic improvements in just three weeks!
The fact that you noticed a difference within the first week and it's continued to build is exactly what we love to hear. No more bloating, gas, or belching after years of suffering is life-changing, and we're so glad you gave Biome Protect a try. Benefits often continue to build over the next few months as your gut continues to heal and rebalance. Welcome to the Adapt Naturals family. We're so glad you're here, and we're honored to be part of your gut health journey.

P
Patricia Hough
Really good product!

I decided to try Biome Protect because the probiotic I had been taking for years wasn't helping me with constipation at all. I bought one package of Biome Protect and started with just one capsule instead of the recommended 2 capsules a day. I started to notice an improvement almost right away! I decided to stay with one capsule a day since my bowel movements became more regular and actually looked like the healthy bowel movement picture on the gastroenterology specialist's office chart. I never expected to see such a dramatic change in my bowel movements. Right before I finished the first package, I signed up for a subscription of one package every 2 months. I am more than satisfied with this great product!

Hi Patricia,

That's fantastic! We're so thrilled to hear about your experience with Biome Protect!
It's wonderful that you listened to your body and adjusted the dosage to what works best for you—starting with one capsule and seeing such quick, noticeable improvement is exactly the kind of result we love to hear about. And the fact that you're seeing consistently healthy bowel movements that match the gastroenterology chart? That's really encouraging!
We're so glad you found a rhythm that works perfectly for you with the subscription. Thank you for trusting Biome Protect and for sharing your story—it means the world to us. Here's to continued digestive health and feeling your best!

E
Esther Geranton
Biome protect 🤗

I started taking Biome Protect about a month ago,and I couldn’t be more pleased with it. I used to be dreading what my bm would be every day, constipation! Diarrea? Things have changed for the best, I was pleasantly surprised and shocked about a week of Biome Protect to have a normal bm. I will be forever thankful for Dr Chris Kresser

Hi Esther,

Thank you so much for sharing this wonderful experience! We're absolutely thrilled to hear that Biome Protect has made such a meaningful difference for you—and in just one week! No longer having to dread your daily digestive experience is such a huge quality of life improvement.
The Bacillus coagulans probiotic in Biome Protect, along with the tributyrin, PreforPro prebiotic, and polyphenols, work together to support gut health and healthy digestive function. It sounds like your microbiome is responding beautifully to the comprehensive 4-in-1 approach.
We're so grateful that Chris's formulation is helping you feel your best, and we appreciate you being part of the Adapt Naturals community. Reviews like yours truly inspire us! Take good care.

K
K
Great product!

I feel less bloated and more energy since taking it. I also have always loved pomegranates for a million reasons and this is just one more that they help out microbiome. So cool!

Hi K,
That’s fantastic to hear! And yes—pomegranate extract is one of our favorite microbiome supporters. Its polyphenols are like fuel for beneficial bacteria. We’re thrilled to see those benefits showing up in your body!

B
Beverly Miller
Like but…..

I’ve only been using the Biome Protect for a couple weeks and I’m already seeing slight improvement in my bowel movements.
However, I noticed an empty capsule and loose powder in the bag. So I’m a bit disappointed in losing some precious product.

Hi Beverly,

Thanks so much for your review. We’re glad to hear you’re starting to see digestive improvements—even small shifts early on can signal progress! We’re sorry to hear about the capsule issue and appreciate you bringing that to our attention. If you'd like a replacement or help with this, please reach out to our support team.

Wishing you continued improvement!

A
Andrew Bufkin
Biome Protect is Amazing!

A lot of gut relief so far and much healthier poop

Hi Andrew,

Thanks for sharing your experience with Biome Protect! Great to hear you're getting gut relief and seeing positive changes in your digestion already. That improved stool quality is actually one of the most common benefits our customers report, and it's a good sign that the product is working well for your microbiome.

M
Marisa Moon
Next-Level Probiotics (noticeable results!)

I was surprised how noticeable the results were for me early on. I had a more stable mood even though I was in my late luteal phase, and I was feeling more energized in the mornings. I took this first thing in the morning, and I could tell fasting came more easily than it has been lately. This is probably thanks to the bioavailable butyrate they've added. How cool! As a fasting coach, I also looked into the fruit extracts to be sure those quantities wouldn't disrupt ketosis or fasting (they don't even come close).

What's more is that the new form of prebiotics they have incorporated are as effective as 10x this dose but without those pesky side effects commonly experienced, such as gas and bloating. I was able to start with a full dose on day one and no gas. That's great!

This is the first probiotic supplement I have tried that I've actually felt a noticeable difference. My bowel movements were completely normalized since I started too. I'll definitely be telling clients about this, and ordering more for myself.

Hi Marisa,

Thanks for sharing your experience with Biome Protect! It's fantastic to hear you noticed such early results with mood stability, morning energy, and easier fasting - especially as a fasting coach yourself.

The normalized bowel movements and lack of gas/bloating (even starting at full dose) are exactly what we hoped for when formulating with the specific strains and prebiotics. Your professional perspective on the product's benefits is particularly valuable.

Thanks again for your thoughtful review and we look forward to hearing about your future experience with Biome Protect!

C
Cara Molina
Smoothest skin ever and better digestion!

I've been trying to think why is my skin glowing and so much clearer all of a sudden? Then I realized it's ever since I started taking biome protect! I think it's definitely helped balance out my gut micro biome because I no longer get the hormonal breakout that I always get every month and my digestion has also improved. I used to experience a little bit more bloating after certain foods and I no longer seem to have that problem so thankful for this product!

Hi Cara,

Thanks for sharing those unexpected skin benefits! It's amazing how your breakouts have cleared up - really shows that gut-skin connection in action. And less bloating is always a win!

We love when customers notice improvements beyond what they were originally looking for. The skin clearing up is a great sign that Biome Protect is helping balance your gut microbiome like it's designed to do.

S
Skai Vingilys
My gut health is improving and energy is increasing!

I’ve struggled with gut issues for most of my life, and things got ten times worse after contracting COVID four years ago. I was extremely bloated and felt like I couldn’t eat anything without a reaction. When I say bloated, I literally looked nine months pregnant, I will attach my before and after pictures. I tried countless supplements and different probiotic brands, but nothing seemed to help. After researching new supplements, I discovered Adapt Naturals, and I can finally say that my bloating is almost gone after just a few weeks. I have much less gas, and my painful gas is completely gone. My bowel movements have become more regular (2-3 times a day, compared to 1 times before).
I also suffer from chronic fatigue, and I’ve noticed an improvement in my energy levels. I need fewer breaks throughout the day and can work longer, which was a real struggle for me before. Additionally, I feel calmer, I’m not crying as much, and I feel more emotionally balanced overall. I’ll definitely continue taking these supplements, and I can’t wait to see my progress after a few more months! I also take other Adapt Naturals supplements to support my health, including Omega, Beef Organs, and Colostrum.

Hi Skai,

Thanks for sharing your incredible gut health journey! Going from extreme bloating to finding real relief is huge. Those improvements you're seeing - reduced bloating, better digestion, more energy, and even emotional balance - really show how connected gut health is to our overall wellbeing.

After trying so many products without success, we're glad you found something that actually works. Many of our customers combine Biome Protect with Omega, Organ, and Colostrum+ like you're doing - they work really well together for comprehensive support.

Keep us posted on your continued progress! Stories like yours remind us why we do what we do.

C
Carolina Hilderbrand
Game changer for my kids and I!

After struggling with gut issues for years, my little girls started to struggle too. We started using Colostrum+ from Adapt for a while, and we’ve loved it! When we got the opportunity to try Biome Protect, I knew we had to try it, and I’m so happy we did. It took about 2 weeks for me to really feel it, but my digestion has greatly improved, and we didn’t get sick at all after hanging out with sick cousins a couple weeks ago! Can’t wait to see how we feel after a few months!!

Hi Carolina,

Thank you for sharing your family's journey with both Bio-Avail Colostrum+ and Biome Protect! It's wonderful to hear how these products are helping both you and your daughters with gut health and immune support.

While some people notice changes quickly, others find it takes a couple of weeks to experience the full benefits as the 4-in-1 formula works to support a healthy gut ecosystem. And it's fantastic that your immune systems stayed strong even after exposure to illness!

Please keep us posted on how you and your girls continue to feel over the coming months. Your experience could really help other families looking for natural solutions for gut health!

M
Melanie
Game-Changing Experience!

I’ve been trying Adapt Naturals Biome Protect, and it’s truly unlike any other gut health supplement I’ve used. Drawing on Chris Kresser’s 15 years of clinical expertise, this 4-in-1 formula combines PreforPro® prebiotic, LactoSpore® Bacillus coagulans probiotic, CoreBiome® tributyrin, and a specialized polyphenol blend for a comprehensive approach to digestive and overall health. I love that it avoids the typical side effects of fiber-based prebiotics and ensures the probiotics actually survive stomach acid to reach the intestines. Since starting Biome Protect, I’ve noticed improved digestion, more energy, clearer skin, and even better focus. Plus, it’s shelf-stable, eco-friendly, and thoroughly tested for purity, making it a product I trust and highly recommend.

Hi Melanie,

Thank you for this review of your experience with Biome Protect! We're thrilled to hear how it's improving not just your digestion, but also your energy, skin health, and mental clarity. This illustrates how supporting gut health can have wide-ranging benefits throughout the body.

You've highlighted some key points that make Biome Protect unique - particularly how we've addressed common issues with traditional gut supplements. The PreforPro® prebiotic works effectively at a much lower dose than fiber-based prebiotics, helping avoid the bloating and discomfort that many people experience. And the spore-forming LactoSpore® probiotic is specifically chosen to survive the journey through stomach acid.

Thank you for taking the time to share such detailed feedback about your experience!

G
Gregory Smith
Gut health

I actually think I’ve seen an improvement