In a randomized, double-blind study, participants saw over 60% less bloating.
In a 2023 randomized, placebo-controlled study, Bacillus coagulans MTCC 5856 (LactoSpore®) reduced functional gas and bloating scores by 65.5% over 4 weeks — versus 11.5% in the placebo group (P<.001).* This is the probiotic strain inside Biome Protect. It’s one of four clinically studied ingredients. We’re showing you the evidence for each one.
"I formulated Biome Protect because nothing on the market did all four jobs at once."
— Chris Kresser, M.S. · Functional medicine practitioner · 15 years clinical experience · 1M+ patients reached
Try Biome Protect risk-free for 90 days.
If it doesn’t work — and we mean actually work — we’ll refund every penny you spent. Every capsule. Even if the bottle is empty. No questions. No returns. No calls.
Biome Protect
Includes 1 FREE Bio-Avail Colostrum+
Free Bio-Avail Colostrum+ included
- No commitment. Modify, pause, or cancel anytime
- 10% off subsequent orders
- FREE Bio-Avail Colostrum+ with first delivery ($69.94 value) when you subscribe to 60 or 90-days
Most probiotics do one job. This does four.
Restores beneficial bacteria
A clinically studied spore-forming probiotic that survives stomach acid and reaches your colon alive — where it does the work.
LactoSpore® · B. coagulans MTCC 5856 · 6B CFU
Feeds them without the bloat
A non-fiber prebiotic that selectively nourishes good bacteria, without the gas, bloating, or 'die-off' that fiber-based prebiotics cause.
PreforPro® · Bacteriophage prebiotic
Strengthens your gut barrier
Tributyrin: a postbiotic short-chain fatty acid that fuels the cells lining your intestines and helps repair the gut barrier from the inside.
CoreBiome® · Clinically studied tributyrin
Reduces irritation
A targeted polyphenol blend that helps calm gut irritation and supports a healthier microbial balance long-term.
Polyphenol complex · pomegranate, cranberry, green tea
What customers report in the first three months
"My longtime constipation is GONE. I’m digesting my food better. I have more energy. My mood is better."
Jill M. Verified buyer
"I’ve tried Seed and Pendulum. Biome Protect is better than anything I’ve ever tried."
Sarah H. Verified buyer
"For the first time in years my digestive issues and bloating are gone."
Mary J. Verified buyer
"After years of not being able to take any probiotic, I cautiously tried Biome Protect. It’s the only one that’s ever truly helped."
Stephanie V. Verified buyer
If you’ve tried probiotics before — here’s what’s different.
Four clinically studied ingredients. No fillers. No fluff.
Probiotic
LactoSpore®
Bacillus coagulans MTCC 5856
A heat-stable, spore-forming probiotic strain that survives stomach acid and reaches the colon alive. Backed by 30+ clinical studies for IBS-related bloating, gas, and bowel regularity.
Prebiotic
FortiPhage™
Bacteriophage prebiotic blend
Selectively targets and reduces gut pathogens while making room for beneficial bacteria — without the fiber-related bloating that derails most prebiotics.
Postbiotic
CoreBiome®
Tributyrin (short-chain fatty acid)
A clinically studied form of butyrate that fuels gut barrier cells, strengthens the intestinal lining, and helps reduce gut inflammation.
Polyphenols
Polyphenol complex
Pomegranate · cranberry · blueberry · grape
A targeted blend of polyphenols that further nourishes good bacteria and supports microbial diversity over the long term.
After 15 years treating thousands of patients, I built the gut formula I wished existed.
I’m Chris Kresser. I’m a functional medicine clinician, not a supplement marketer. For 15 years I worked with patients struggling with chronic gut issues — many of them after they’d already tried everything else their doctors could offer and everything the supplement industry could sell them.
What I kept seeing is that most probiotics on the market are designed to look impressive on a label, not to work in a body. They use strains that don’t survive stomach acid. They add fiber-based prebiotics that cause bloating in the very people who need help most. And they completely ignore the postbiotics and polyphenols that actually rebuild the gut barrier.
I formulated Biome Protect because I was building it for my patients — and eventually for myself. Every ingredient is clinically studied. Every dose matches the research. No proprietary blends, no filler, no guesswork.
When a clinical trial showed 60% reduction in bloating with the bacteriophage prebiotic at its core, it confirmed what I was already seeing in my practice. The science caught up.
If you’ve tried other probiotics and felt let down, I’m not surprised. I built this for you.
— Chris Kresser, M.S. · Functional Medicine Practitioner · Founder, Adapt Naturals
Your gut didn’t break in a week. Here’s the realistic timeline.
Some people notice less bloating after meals within the first few days. Others feel a settling-in period. Both are normal.
Bowel movements typically become more regular and complete. Bloating reduces noticeably.
Most customers report ‘baseline gut feel’ improving, with fewer flare-ups, less reactivity to foods.
Gut barrier integrity, energy, mood, and skin often follow. This is where the deeper changes happen.
If you’ve been let down before, read these.
"I have a lot of GI issues after years of antibiotic treatment for Lyme — multiple food sensitivities, leaky gut, candida, SIBO, constipation, bloating. In short, Biome Protect has changed my life. My longtime constipation is GONE. I’m digesting my food better. If I could only choose one supplement, this would be it."
"I have my diet and lifestyle dialed. I’m approaching menopause and have Hashimoto’s so I support my body with probiotics. I’ve tried Seed and Pendulum which were good for a while, but Adapt’s Biome Protect is better than anything I’ve ever tried. I recommend it to all of my clients, friends, and family now."
"After getting SIBO 12 years ago and not knowing what it was for years, I tried a lot of gut supplements. I especially experimented with probiotics — but they made my condition worse. After years of not being able to take any, I cautiously tried Biome Protect. It’s been the only probiotic I’ve ever taken that truly helps."
Trusted by Clinicians Worldwide
Healthcare practitioners stake their professional reputation on products that actually work.
Dr. Mir Ali, MD
Verified Clinician
"I strongly recommend Biome Protect for patients seeking support for digestion and bloating. Because Bacillus coagulans can survive stomach acid, it is able to reach the intestines where it can do its job."
Dr. Donald Nicholas, MD
Verified Clinician
"I like this blend for patients interested in a supplement that can influence gut and skin health at the same time. Gut-friendly bacteria are associated with a healthy gut barrier."
Teresa Byrd, CNS
Verified Clinician
"I highly recommend Biome Protect, and I believe it can be well-suited for those who bloat easily. Gut balance depends on how bacteria interact and not just how many grow."
See What Real Customers Are Saying
Everything you might be wondering.
Most probiotics fail for one of three reasons: the strains don’t survive stomach acid, the prebiotic causes bloating, or there’s no postbiotic to actually heal the gut barrier. Biome Protect uses a spore-forming probiotic that survives acid, a non-fiber prebiotic that doesn’t bloat, and adds tributyrin and polyphenols for full-spectrum support. That’s why it works for people who’ve tried everything else.
Most customers notice less bloating within the first week and more regular bowel movements within 2–3 weeks. Deeper changes — gut barrier integrity, energy, skin, mood — typically show up in months 2–3. We recommend giving it at least 60 days. That’s why our guarantee is 60 days — long enough to know if it works for you.
Almost never. Unlike fiber-based prebiotics, the prebiotic in Biome Protect (FortiPhage™) doesn’t ferment in the gut, so it doesn’t cause the gas, bloating, or die-off reactions that derail most probiotics. If you have an extremely sensitive system, we recommend starting with one capsule every other day for a week, then ramping up.
No. The probiotic strain in Biome Protect (Bacillus coagulans) is spore-forming and shelf-stable. It survives heat, stomach acid, and time. You can travel with it, leave it in a hot car, and it still works.
Yes. Biome Protect pairs especially well with our bio-Avail Colostrum (which is why we include it free with subscriptions). If you’re on prescription medication, check with your doctor, but there are no known interactions with the ingredients in Biome Protect.
90 days, money-back, no questions asked, even if the pouch is empty. We’d rather refund you than have you keep something that didn’t work.
Two reasons. First, gut healing happens over months, not weeks. Most customers see the deeper benefits at month 2 and beyond. Second, subscribers save 15%, get free bio-Avail Colostrum with their order, and free shipping. You can pause, skip, or cancel anytime in one click.
Yes. Every batch is tested by an independent lab for purity and potency. Certificates of Analysis are available here: https://adaptnaturals.com/pages/third-party-testing