Finally, A Gut Health Solution That Actually Works—4-in-1 Clinical Formula

The only complete microbiome support with probiotics, prebiotics, postbiotics AND polyphenols for results you can feel in days, not months

Finally, A Gut Health Solution That Actually Works—4-in-1 Clinical Formula
Clinician-Formulated | 3rd Party Tested | 60-Day Guarantee | Free Shipping
★★★★★ 4.7/5 (142 verified reviews)

Starting at $52.14/month (With 10% Subscribe & Save)

Choose Your Stack & Save Up to 59%
Why Biome Protect is Different ↓

5 Science-Backed Benefits in 30 Days or Less

1

Eliminate Bloating & Digestive Discomfort

Biome Protect's 4-in-1 formula balances your microbiome and nourishes gut cells directly. Customers report dramatic improvements in bloating, gas, and irregularity—often within days.

"Having spent years in the holistic health space, I’ve come across only a handful of probiotics that truly deliver results—but this one is on a whole new level. It combines both prebiotics and probiotics, making it a game-changer for gut health! Since adding it to my routine, I’ve noticed reduced bloating, improved energy, and even glowing skin. This supplement has been a total win for me! Paired with colostrum+, I feel completely set on my wellness journey." - Lauren, Verified Buyer
2

Boost Mental Clarity & Focus

Your gut produces 90% of your body's serotonin. By optimizing your microbiome with targeted probiotics and postbiotics, you'll experience clearer thinking and improved mood.

"I loved this product. Immediately noticed a shift in my digestion and felt more clarity." - Martha, Verified Buyer
3

Strengthen Your Immune Defense

With spore-based probiotics that actually survives stomach acid plus immune-training prebiotics, you'll build resilient immunity from the inside out.

"Biome Protect is an incredible product- it’s like getting four supplements in one! I love that it supports digestion, immunity, and overall resilience. I’ll be using this myself and with clients." - Oana, Verified Buyer
4

Natural, Sustained Energy

By healing your gut and optimizing nutrient absorption with butyrate-producing postbiotics, you'll experience steady energy without crashes.

"Biome Protect has changed my life! My longtime constipation is GONE. I’m digesting my food better. I have more energy. My mood is better—and I’d even say I have less anxiety." - Jill, Verified Buyer
5

Clearer Skin & Enhanced Vitality

Targeted polyphenols from ancestral sources boost vitality and support your gut-skin axis for a clearer, more radiant complexion.

"After suffering from gut issues, trying a lot of different supplements and doing research I decided to try Bio-Avail Colostrum+ and Biome Protect. I am about 6 weeks in and not only are my gut issues greatly improved, my skin, hair and nails look fabulous." - Janet, Verified Buyer

Why Your Current Gut Health Approach Isn't Working

If you've tried probiotics before and felt disappointed, you're not alone. After 15 years in clinical practice, I kept hearing the same frustrating story from patients.

They were taking multiple supplements—probiotics, fiber, digestive enzymes—spending hundreds of dollars monthly, yet still struggling with:

  • Persistent bloating and digestive discomfort
  • Unpredictable energy crashes
  • Brain fog that wouldn't clear
  • Skin issues that seemed unrelated to diet
  • Mood swings and anxiety
  • Compromised immune function

The truth? Most gut health approaches fail because they only address one piece of the puzzle. Traditional probiotics die in stomach acid. Fiber prebiotics cause more bloating. And nobody talks about postbiotics or targeted polyphenols.

After seeing thousands of patients waste money on incomplete solutions, I knew there had to be a better way...

Introducing Biome Protect: The Clinical-Grade 4-in-1 Formula

Introducing Biome Protect: The Clinical-Grade 4-in-1 Formula

This deep understanding, gained from treating thousands of patients and training hundreds of clinicians, led me to create Biome Protect—the first Gut Health 3.0 formula that combines all four essential elements in one comprehensive solution.

What Makes Biome Protect Different:

Spore-Based Probiotics Survives stomach acid (unlike 95% of probiotics)
Non-Fiber Prebiotics Work at 1/300th the dose without bloating
Postbiotic Butyrate Direct fuel for gut cells
Targeted Polyphenols From cranberry, pomegranate, grape & blueberry
Professional Quality Clinician-formulated with premium ingredients
Complete Solution Replaces an entire cabinet of gut supplements
Third-Party Tested Every batch verified for purity and potency
Made in USA | GMP Certified | Non-GMO

The Biome Protect Difference: It's Not Just More, It's Better

Through years of clinical research, I discovered why traditional gut health fails—and created the breakthrough my patients needed.

Traditional Approach Premium Probiotics Biome Protect
Basic probiotics that die Survives stomach acid Spore-based + 3 more elements
Fiber that causes bloating Some prebiotic benefit Non-fiber prebiotics
No postbiotic support Basic formula Complete postbiotic fuel
Minimal results Some benefits Transformative results

The Clinical Breakthrough: Biome Protect is the first formula to combine probiotics, prebiotics, postbiotics, AND polyphenols—creating the complete microbiome support your gut actually needs.

Real Transformations from Real People

★★★★★
Mary, Verified Buyer
"I’ve only been taking Biome Protect for a week and already notice significant results. I was struggling with bloating and constipation after meals, and within a few days have much healthier, easier, and fuller BMs. I also feel a little more energy after my meals. Looking forward to more benefits with longer use."
★★★★★
Jasmine, Verified Buyer
"I have been told I have IBS so I've struggled with bloating and constipation for years. I tried [competitor probiotic] for a few months but it seemed to just stop working as well. I tried Adapt because I like that its not just about the gut but focuses on the gut. Its been a few weeks and it's already working better. I'm regular, no bloating and I feel good all around!"
★★★★★
Paula
"I definitely noticed a difference since starting Biome Protect and believe it’s due to the type of probiotic strain used. Daily bowel movements come easier, are better formed and bloating and gut uneasiness lessened. So glad to have tried this product that I’ll continue using."

Join 15,000+ people who have transformed their health with Adapt Naturals

Meet Chris Kresser, your
Trusted Health & Wellness Guide

Founder & Functional Medicine Clinician

  • Globally renowned expert with over 15 years of experience
  • Dedicated to helping people improve their health by addressing modern challenges and nutrient gaps

Author & Educator

  • Treated thousands of patients
  • Trained more than 2,000 healthcare professionals
  • Gained valuable insights into functional medicine and nutrition

As Seen In

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🌿 GUT HEALTH TRANSFORMATION

Complete Microbiome Support for Digestive Health & Immune Function

Complete Microbiome Support for Digestive Health & Immune Function

SAVE $98.00
✓ FREE Bio-Avail Colostrum+
$98.00 TOTAL SAVINGS
Biome Protect
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FREE Bio-Avail Colostrum+
Essential Gut Health
1 Biome Protect PLUS 1 FREE Bio-Avail Colostrum+
$81.00
Biome Protect $81.00
Bio-Avail Colostrum+ (FREE) -$98.00
Total value: $179.00
Your price today: $81.00
You save: $98.00 (54%)
*First order discount applies to today's purchase only. Subscribe & Save 10% applies to all future deliveries.
Free gift not included in recurring subscription orders.
  • FREE Bio-Avail Colostrum+
  • Balances microbiome
  • Eliminates bloating
  • Boosts mental clarity
  • 60-day money-back guarantee
Best Value
SAVE $251.79
FREE Bio-Avail Colostrum+ Plus FREE Shipping
$251.79 TOTAL SAVINGS
Biome Protect
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Biome Protect
Biome Protect
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Biome Protect
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Biome Protect
FREE Bio-Avail Colostrum+
Complete Gut Restoration
6 Biome Protect + 1 FREE Bio-Avail Colostrum+
$340.20
Biome Protect x6 $486.00
Bio-Avail Colostrum+ (FREE) -$98.00
30% Bundle Discount -$145.80
FREE Shipping -$7.99
Total value: $591.99
Your price today: $340.20
You save: $251.79 (42%)
*First order discount applies to today's purchase only. Subscribe & Save 10% applies to all future deliveries.
Free gift not included in recurring subscription orders.
  • FREE Bio-Avail Colostrum+
  • FREE Shipping
  • 60-day money-back guarantee

Building Your Complete Gut Restoration Protocol

While Biome Protect provides the essential 4-in-1 foundation for gut health, some patients in my clinic needed additional support for complete restoration. After years of clinical practice, I formulated complementary products that create a comprehensive healing system when combined with Biome Protect.

About your FREE Bio-Avail Colostrum+: The Gut Barrier Shield

For patients with severe gut permeability issues, I discovered that adding colostrum accelerated healing dramatically. Bio-Avail Colostrum+ provides:

  • Immunoglobulins that neutralize harmful bacteria
  • Lactoferrin for natural antimicrobial support
  • Growth factors that directly repair intestinal lining
  • Enhanced with beta-glucan for immune training

When combined with Biome Protect, it creates powerful synergy: Biome Protect optimizes your microbiome while Bio-Avail Colostrum+ repairs and seals your gut barrier.

Product image

"I'm excited about Adapt Naturals and Bio-Avail Multi. Chris is a leading clinician, educator, and researcher in the Functional Medicine space. I've learned a lot from him about nutrition and supplements over the years, and I know his products are fueled by high-quality, evidence-based ingredients you can trust."

Dr. Mark Hyman MD

14-time New York Times best selling author and founder of the Cleveland Clinic Center for Functional Medicine

"Chris Kresser is one of the sharpest minds in the functional / integrative medicine space. I have reached out to Chris many times when working to unravel my own health journey and his insights have always been incredible. Given all that, I'm super excited for the release of Adapt Naturals line of supplements, especially Bio-Avail Multi. Chris and I are aligned in that we believe the bulk of our nutrition should come from whole, minimally processed foods, but we also recognize that the right supplement, at the right time can 'change everything.'"

Robb Wolf

Former research biochemist and 2-time New York Times bestselling author of The Paleo Solution and Wired To Eat.

"I can't think of a better person to formulate supplements than Chris Kresser. I trust his ability to skillfully combine ancestral wisdom with modern science and cutting-edge research. Taken together, the products offer a well-rounded and complete way to boost your nutritional status. I am excited about this high-quality, comprehensive new product line - I strongly recommend it!"

Dr. Akil Palanisamy MD

Harvard-trained physician, author, speaker, and holistic medicine expert in integrative and functional medicine

"I trust Chris Kresser with my life, and you will too."

Sara Gottfried MD

Harvard Trained Physician and New York TimesBestselling author of The Hormone Cure

60-Day Money Back Guarantee

60-Day Money Back Guarantee

We're confident you'll love our products, but if you're not completely satisfied, we offer a 60-day, 100% money-back guarantee on all purchases. Simply contact us for a full refund, no questions asked. Buy with confidence knowing you're covered by our guarantee.

The Adapt Naturals Standard

The Adapt Naturals Standard

In our increasingly toxic world, the last thing you want to worry about is a lot of artificial junk in your supplements. Adapt Naturals supplements are made with the cleanest possible ingredients, without gluten or GMOs. Our products are manufactured in a U.S. facility that meets the NSF’s rigorous GMP regulatory standards.

Third Party Lab-Tested

Third Party Lab-Tested

At Adapt Naturals, all of our products are third-party tested and validated, and we are always happy to share these results with customers. We want you to have full confidence that you’re getting exactly what you think you are with each purchase.

Learn More

Your Questions Answered

Take 2 capsules daily, preferably with a meal. For best results, take consistently every day.

Some people may notice improvements in digestion and energy within a few days. However, for full benefits, we recommend taking Biome Protect consistently for at least 30-60 days.

No, Biome Protect is shelf-stable and does not require refrigeration. Store in a cool, dry place.

Yes, Biome Protect is designed to complement other supplements, including other probiotic strains. However, if you're taking any medications, please consult with your healthcare provider before starting any new supplement regimen.

If you are pregnant, nursing, or taking blood thinners or anti-coagulant medications, please consult with your healthcare provider before using Biome Protect.

Yes, Biome Protect is formulated for safe, long-term use. The ingredients are naturally occurring compounds that support overall gut health and wellness.

Yes, all Adapt Naturals products, including Biome Protect, undergo rigorous third-party testing for purity and potency. Most importantly, we transparently share these results with our customers by posting Certificates of Analysis (CoAs) and test results on our website. This level of openness is almost unheard of in the supplement industry. It allows you to see exactly what’s in the product you’re putting into your body.Click here to view the most recent CoA and test results.

Customer Reviews

Based on 158 reviews
83%
(131)
8%
(13)
3%
(5)
2%
(3)
4%
(6)
D
Dallas Bogert
I can feel the difference

I’ve been taking biome protect for two weeks now the first week I didn’t feel any different the second week I can feel the difference as things are working yet. It takes a while for things to work. My Microbiome was not wrecked in one day. It’s happened overtime so I have to give time to get my health back and these have been helping truly, I feel a difference within those first two weeks less bloating, more consistent bathroom times and all I can do is hope that it gets better and better the longer I take them thank you.

Hi Dallas,

Thank you for such a thoughtful, realistic perspective! You’re absolutely right—rebuilding the microbiome takes time, and consistency is key. We designed Biome Protect with carefully selected probiotic strains, prebiotics, postbiotics and gut-healing polyphenols to support long-term digestive balance, reduce bloating, and improve regularity. We’re thrilled you’re already feeling the shift and rooting for even more progress ahead!

I
Ivellisse Quinones
Biome Protect

I bought this supplement and I have been using it for about two (2) weeks. I have noticed that I don't have that urge to snack frequently and feel satisfied longer. It has helped me to regularize with my gut. I feel with more mental alertness and less tired during the day. Thanks.

Hi Ivellisse,

This is wonderful feedback—thank you! Biome Protect was formulated not only to support gut regularity but also to positively influence satiety and energy through the gut-brain axis. We’re so glad you’re experiencing steadier energy, less snacking, and improved focus. Keep us posted on your journey!

S
Sarah H.
Better than anything I’ve tried.

I have my diet and lifestyle dialed. I am approaching menopause and have hashimotos and rosacea so I like to support my body with probiotics. I’ve tried Seed and pendulum which were good for a while but Adapts Biome Protect is better than anything I’ve ever tried. I recommend it to all of my clients, friends and family now. 5 stars!

Hi Sarah,
Your review truly made our day — thank you! Biome Protect combines probiotics, prebiotic, polyphenols, and postbiotics to support gut balance in a holistic way. We’re honored that it’s been so effective for you and that you’re sharing it with your community. Your trust means the world to us.

j
jess
Biome Protect

recommended to me by my herbalist for chronic IBS symptoms and symptoms that were associated with an imbalance in microbiome. I felt shifts after the first day- less bloat and heaviness in the gut, less digestive distress overall, and increase in hunger came back, shift in mood, heavy mental states also shifted, and i noticed an increase in stamina and energy levels. i have tried all things nutrition and all kinds of products and this one by far has had the most positive impact. i feel like my gut is finally in a healing and recovery mode. i will def by this again.

Hi Jess,

Your story is so inspiring! Thank you for sharing it in such detail. We formulated Biome Protect with targeted probiotics, prebiotics, postbiotics and polyphenols to rebalance the gut, ease digestive distress, and support the gut-brain connection. It’s incredible to hear how quickly you felt shifts in your energy, mood, and overall digestive comfort. We’re honored to be part of your healing journey and we hope to continue to be! Welcome to the Adapt Naturals family!

T
Tyler Holt
Best feeling gut ever!

My gut has never felt better! Thank you!

Hi Tyler,
This makes us so happy to hear — thank you! We’re thrilled Biome Protect is helping you feel your best!

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