Rebuild your gut. Recharge your immunity. Restore your glow.
A 3-in-1 grass-fed colostrum formula with clinical-dose lactoferrin and Wellmune® beta-glucan. Built to seal the gut barrier, strengthen immunity, and restore the skin, hair, and nails that follow.
"After 15 years in clinic, I saw that gut barrier repair was the one piece probiotics couldn't do. This is the colostrum I wished existed."
— Chris Kresser, M.S. · Functional medicine practitioner · 15 years clinical experience · 1M+ patients reached
One scoop. Three compounds. Four ways it works.
Seals the gut barrier
Bovine colostrum's growth factors and immunoglobulins repair the tight junctions between intestinal cells. That closes the gaps that let toxins, food particles, and inflammation leak into your bloodstream.
2.5g whole grass-fed colostrum · 25% IgG guaranteed
Strengthens immunity
Clinical-dose lactoferrin pairs with colostrum's natural antibodies to support your body's first line of defense. The result: you get sick less often, recover faster when you do, and stay steadier through seasonal challenges.
100mg Bioferrin® lactoferrin · 30x more than colostrum alone
Restores skin, hair, and nails
Through the gut-skin axis, colostrum's growth factors (EGF, IGF-1) support your body's collagen production. That means smoother skin, stronger hair, and nails that stop peeling. Often within 4 to 8 weeks.
EGF + IGF-1 growth factors from whole colostrum
Trains your immune cells
Wellmune® beta-glucan is the most clinically studied immune ingredient in the world. It primes your innate immune cells to respond faster to challenges without overreacting to harmless triggers.
250mg Wellmune® beta-glucan · 25+ clinical trials
What customers experience in the first few months
"My immune system is 'immune' to the people around me who have been sick this past month."
Stephanie R. Verified buyer
"I've taken colostrum many times over the years for my gut, and I've never noticed a benefit until this one."
Deena T. Verified buyer
"My skin has improved. Less crepe-like and more vibrant. I could see the changes in less than three weeks."
Stephanie S. Verified buyer
"I have terrible IBS with bouts of constipation and diarrhea. Colostrum does the job. I'm much more regular."
Andee L. Verified buyer
If you've tried colostrum before, here's what's different.
Three clinically studied compounds. One complete formula.
Colostrum
Whole grass-fed bovine colostrum
25% IgG guaranteed · third-party tested every batch
Sourced from US grass-fed, pasture-raised cows. Never given hormones or GMOs. Whole colostrum (not skim) means the natural fats stay intact to protect the fragile immunoglobulins and growth factors during digestion. The clinical dose used in published research.
Lactoferrin
Bioferrin® lactoferrin
Iron-binding glycoprotein
Works alongside colostrum's natural antibodies to support your body's immune defenses. At 100mg, this is 30x more lactoferrin than colostrum naturally contains. The dose levels associated with measurable immune benefits.
Beta-glucan
Wellmune® beta-glucan
From baker's yeast (Saccharomyces cerevisiae)
The most clinically studied immune ingredient in the world. Over 25 published human trials. Trains your innate immune cells to respond faster to challenges without overreacting to everyday triggers.
For 15 years I watched colostrum work where everything else failed. So I built the version that delivers.
I'm Chris Kresser. For more than a decade I've worked with patients whose gut issues didn't respond to probiotics, elimination diets, or standard supplements. They needed something that could repair the gut barrier itself, not just feed the bacteria sitting on top of it.
The patients who transformed were the ones taking colostrum, lactoferrin, and beta-glucan together. The combination worked when individual products didn't. But that meant buying three separate products from three companies, spending $100 to $150 a month, and hoping each one was at a clinical dose.
Patient after patient asked the same question: "Isn't there one product that has all three?" There wasn't. So I built it.
Bio-Avail Colostrum+ delivers what I saw work in clinic over more than a decade. All three compounds, at the doses that produced results, in forms your body can absorb, from sources you can trust.
Not to educate people about colostrum. To give them the version that works.
— Chris Kresser, M.S. · Functional Medicine Practitioner · Founder, Adapt Naturals
The gut comes first. Then immunity. Then the mirror.
Less bloating after meals. More regular, complete bowel movements. Gut feels calmer.
You stop catching every bug that goes around. When you do get sick, you bounce back faster.
Subtle skin changes. Smoother texture, less crepey. Hair starts feeling fuller. Nails stop peeling.
Visible glow. New hair growth where it had thinned. The compliments start. People ask what changed.
If colostrum hasn't worked before, read these.
"After trying yogurt, probiotics, kefir, kombucha, all the things, I thought I'd never have a normal healthy gut again. I was bogged down with bloating and diarrhea for two years. After about a month on Colostrum+, my guts were changing. I was less gassy and feeling so much better. I'm happy to have finally found my 'cure.'"
"I have been using Adapt Naturals Colostrum for about 9 months now and the difference is amazing. Being with my granddaughter, who would bring every germ home from daycare, I used to catch everything. I have not been sick once in the past nine months. This is HUGE for me."
"I initially bought this product to address gut issues. But my skin has improved noticeably. Less crepe-like and more vibrant. I am a menopausal woman and could see the changes to my skin in less than three weeks. I've recommended this to many friends."
Start strong with the Colostrum+ Welcome Kit.
Everything you need for your first 30 days — included free with your subscription.
Bio-Avail Colostrum+
Includes FREE Welcome Kit ($72 value)
Save 10% on every order
Renews at $62.95 every 30 days. Cancel anytime.
- Save 10% on every order
- FREE Welcome Kit with first delivery ($89 value)
- Modify, pause, or cancel anytime
- 90-day money-back guarantee
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Free storage bottle $7 value -
Frother for the perfect mix $25.99 value -
Tips & tricks ebook $X value
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Free Shipping $7.99 value
Trusted by Clinicians Worldwide
Healthcare practitioners stake their professional reputation on products that work.
Dr. Mir Ali, MD
Verified Clinician
"Colostrum is one of the few supplements I recommend across the board. The combination of immunoglobulins, lactoferrin, and beta-glucan in this formula supports the gut barrier and immune resilience together."
Dr. Donald Nicholas, MD
Verified Clinician
"I appreciate that this formula uses whole colostrum at a clinical dose, not the under-dosed skim products that dominate the market. Patients notice the difference."
Teresa Byrd, CNS
Verified Clinician
"For patients working on gut barrier integrity, colostrum delivers what probiotics alone cannot. This is the version I recommend."
See What Real Customers Are Saying
Everything you might be wondering.
Most colostrum products fail for one of three reasons. The dose is too low (typical products use 500mg to 1g; published research uses 2g+). The colostrum is 'skim' with fats stripped out, which means the fragile immunoglobulins don't survive digestion. Or the IgG content isn't verified. Bio-Avail Colostrum+ delivers 2.5g of whole colostrum with 25% IgG guaranteed and tested every batch. It also adds lactoferrin and Wellmune® beta-glucan, which work alongside colostrum to multiply the effect. That's why customers who tried colostrum elsewhere with no results often see real change with this formula.
Most customers notice gut changes (less bloating, more regular bowel movements) in the first 1 to 2 weeks. Immune benefits typically show up in weeks 3 to 4. The skin, hair, and nail benefits take longer. Usually 4 to 8 weeks for subtle changes and 60 to 90 days for the visible results customers tell us about. Our 90-day guarantee is designed to give you a full three months to see the deeper effects.
Many customers with dairy sensitivities tolerate colostrum well because it's structurally different from milk, naturally low in lactose and casein. That said, colostrum is a bovine product. If you have a confirmed milk allergy (not lactose intolerance), this isn't for you. If you're unsure, start with half a scoop for the first week and ramp up.
One scoop daily, mixed into water, smoothie, coffee, oatmeal, or yogurt. It's nearly tasteless. Most customers take it in the morning, but timing doesn't matter, consistency does. Use it daily for at least 60 days to know whether it's working for you.
US grass-fed, pasture-raised cows. Never given hormones, antibiotics, or GMO feed. Every batch is third-party tested for heavy metals (undetectable), pesticides (below detection), antibiotics (none detected), and potency (confirmed at labeled amounts). Certificates of Analysis are available. Just email support.
90 days, money-back, no questions asked. Even if the pouch is empty. You don't have to return it, just keep it. If it didn't work for you, we'd rather refund you than have you sit on something you won't use.
Because they work better together. Colostrum+ rebuilds the gut barrier. Biome Protect optimizes the bacterial ecosystem inside it. Customers who use both see faster, more complete gut transformation than either alone. We include Biome Protect free with subscription orders because we want you to feel the full effect, not because we're trying to sell you a second product.
Anytime, in one click. Log into your account, hit pause, skip, or cancel. No phone calls, no retention specialists, no friction. You can also change your delivery cadence (every 4, 12, or 24 weeks) from the same page.